Mood Disorders & CBD

As we mentioned in the introduction, serotonin and dopamine levels in the brain are actually directly controlled and regulated by endocannabinoids within the central nervous system’s endocannabinoid system. Several studies, including a recent (2011) publicationin the medical journal Neuropharmacology, have shown this to be the case.

So does this mean, then, that mood swings as a result of chemical imbalance are a direct byproduct of simple endocannabinoid deficiencies, and can be treated with 100% natural medications like CBD oil?

While there’s not yet enough direct evidence to make that claim definitively, it’s appearing more and more likely that this may very well be the case. Several studies and clinical trials, in fact, (including publications in Current Neuropharmacologyand the Journal of Neuroscience) have reiterated the role of the endocannabinoid network in establishing and maintaining mental health and emotional well-being, in addition to acting as “central regulators” of our moods and emotions.

The endocannabinoid system (ECS), if you’re unfamiliar with it, is an innate (naturally occuring inside the human body) network of cannabinoids and cannabinoid receptors that carries out dozens of roles in whole-body homeostasis – from hormonal release in the thyroid gland to neural communication in the CNS and even insulin production in the islet cells of the pancreas. Under normal circumstances, these naturally-occurring cannabinoids (such as anandamide) interact with naturally-occurring cannabinoid receptors (such as the CB-1 and CB-2 receptors) to establish a full range of homeostatic regulation and internal cellular balance.

Thus, when there is a deficiency within the ECS, any number of bodily or neurologic functions might be completely thrown off balance. In these cases, natural cannabis compounds like CBD are needed in order to re-establish and rebuild the proper cell-to-cell interactions that exist within the endogenous cannabinoid/receptor network.